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INRI-seq enables global cell-free analysis of translation initiation and off-target effects of antisense inhibitors

Ribosome profiling (Ribo-seq) is a powerful method for the transcriptome-wide assessment of protein synthesis rates and the study of translational control mechanisms. Yet, Ribo-seq also has limitations. These include difficulties with the analysis of translation-modulating molecules such as antibiot...

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Detalles Bibliográficos
Autores principales: Hör, Jens, Jung, Jakob, Ðurica-Mitić, Svetlana, Barquist, Lars, Vogel, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825163/
https://www.ncbi.nlm.nih.gov/pubmed/36229039
http://dx.doi.org/10.1093/nar/gkac838