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INRI-seq enables global cell-free analysis of translation initiation and off-target effects of antisense inhibitors
Ribosome profiling (Ribo-seq) is a powerful method for the transcriptome-wide assessment of protein synthesis rates and the study of translational control mechanisms. Yet, Ribo-seq also has limitations. These include difficulties with the analysis of translation-modulating molecules such as antibiot...
Autores principales: | Hör, Jens, Jung, Jakob, Ðurica-Mitić, Svetlana, Barquist, Lars, Vogel, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825163/ https://www.ncbi.nlm.nih.gov/pubmed/36229039 http://dx.doi.org/10.1093/nar/gkac838 |
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