TERRA increases at short telomeres in yeast survivors and regulates survivor associated senescence (SAS)

Cancer cells achieve immortality by employing either homology-directed repair (HDR) or the telomerase enzyme to maintain telomeres. ALT (alternative lengthening of telomeres) refers to the subset of cancer cells that employ HDR. Many ALT features are conserved from yeast to human cells, with the yea...

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Detalles Bibliográficos
Autores principales: Misino, Stefano, Busch, Anke, Wagner, Carolin B, Bento, Fabio, Luke, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825167/
https://www.ncbi.nlm.nih.gov/pubmed/36513120
http://dx.doi.org/10.1093/nar/gkac1125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825167/
https://www.ncbi.nlm.nih.gov/pubmed/36513120
http://dx.doi.org/10.1093/nar/gkac1125

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