The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress

Genotoxic agents, that are used in cancer therapy, elicit the reprogramming of the transcriptome of cancer cells. These changes reflect the cellular response to stress and underlie some of the mechanisms leading to drug resistance. Here, we profiled genome-wide changes in pre-mRNA splicing induced b...

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Detalles Bibliográficos
Autores principales: Lemaitre, Florence, Chakrama, Fatima, O’Grady, Tina, Peulen, Olivier, Rademaker, Gilles, Deward, Adeline, Chabot, Benoit, Piette, Jacques, Colige, Alain, Lambert, Charles, Dequiedt, Franck, Habraken, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825188/
https://www.ncbi.nlm.nih.gov/pubmed/36477312
http://dx.doi.org/10.1093/nar/gkac1130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825188/
https://www.ncbi.nlm.nih.gov/pubmed/36477312
http://dx.doi.org/10.1093/nar/gkac1130

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