Cargando…

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress

Genotoxic agents, that are used in cancer therapy, elicit the reprogramming of the transcriptome of cancer cells. These changes reflect the cellular response to stress and underlie some of the mechanisms leading to drug resistance. Here, we profiled genome-wide changes in pre-mRNA splicing induced b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lemaitre, Florence, Chakrama, Fatima, O’Grady, Tina, Peulen, Olivier, Rademaker, Gilles, Deward, Adeline, Chabot, Benoit, Piette, Jacques, Colige, Alain, Lambert, Charles, Dequiedt, Franck, Habraken, Yvette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825188/ https://www.ncbi.nlm.nih.gov/pubmed/36477312 http://dx.doi.org/10.1093/nar/gkac1130

Ejemplares similares

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis
por: Gabriel, Maude, et al.
Publicado: (2015)

The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator
por: Pedrotti, Simona, et al.
Publicado: (2012)

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion
por: Saulnier, Olivier, et al.
Publicado: (2021)

Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism
por: Kim, Sang Hwa, et al.
Publicado: (2016)

Mitochondrial stress induces AREG expression and epigenomic remodeling through c-JUN and YAP-mediated enhancer activation
por: Hino, Yuko, et al.
Publicado: (2022)

Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stress
por: Choi, Soo-Youn, et al.
Publicado: (2013)

Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress
por: McDade, Simon S., et al.
Publicado: (2014)

CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression
por: Park, Su Hyung, et al.
Publicado: (2014)

ATM-mediated ELL phosphorylation enhances its self-association through increased EAF1 interaction and inhibits global transcription during genotoxic stress
por: Pal, Sujay, et al.
Publicado: (2022)

Insulin-response epigenetic activation of Egr-1 and JunB genes at the nuclear periphery by A-type lamin-associated pY19-Caveolin-2 in the inner nuclear membrane
por: Jeong, Kyuho, et al.
Publicado: (2015)

OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency
por: Bernard, Laure D, et al.
Publicado: (2022)

Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress
por: Jeon, Bu-Nam, et al.
Publicado: (2014)

Phosphorylation of p65(RelA) on Ser(547) by ATM Represses NF-κB-Dependent Transcription of Specific Genes after Genotoxic Stress
por: Sabatel, Hélène, et al.
Publicado: (2012)

Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene
por: Mitra, Partha, et al.
Publicado: (2012)

Acid stress response in Escherichia coli: mechanism of regulation of gadA transcription by RcsB and GadE
por: Castanié-Cornet, Marie-Pierre, et al.
Publicado: (2010)

Chromatin disruption in the promoter of Bovine Leukemia Virus during transcriptional activation
por: Colin, Laurence, et al.
Publicado: (2011)

H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing
por: Rondinelli, Beatrice, et al.
Publicado: (2015)

RBM39 Alters Phosphorylation of c-Jun and Binds to Viral RNA to Promote PRRSV Proliferation
por: Song, Yinna, et al.
Publicado: (2021)

The transcription factor Sox5 modulates Sox10 function during melanocyte development
por: Stolt, C. Claus, et al.
Publicado: (2008)

Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex
por: Thiaville, Michelle M., et al.
Publicado: (2008)

S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum
por: André, Gaëlle, et al.
Publicado: (2008)

The CaMV transactivator/viroplasmin interferes with RDR6-dependent trans-acting and secondary siRNA pathways in Arabidopsis
por: Shivaprasad, Padubidri V., et al.
Publicado: (2008)

Expanded binding specificity of the human histone chaperone NASP
por: Wang, Huanyu, et al.
Publicado: (2008)

Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRγ
por: Song, Guisheng, et al.
Publicado: (2008)

Phosphorylation of the carboxy-terminal domain of histone H1: effects on secondary structure and DNA condensation
por: Roque, Alicia, et al.
Publicado: (2008)

Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk
por: Spatuzza, Carmen, et al.
Publicado: (2008)

Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution
por: Ray, Sutapa, et al.
Publicado: (2008)

TAp73β and DNp73β activate the expression of the pro-survival caspase-2(S)
por: Toh, Wen Hong, et al.
Publicado: (2008)

The orphan receptor ERRα interferes with steroid signaling
por: Teyssier, Catherine, et al.
Publicado: (2008)

An intronic microRNA silences genes that are functionally antagonistic to its host gene
por: Barik, Sailen
Publicado: (2008)

Chromatin profiling across the human tumour necrosis factor gene locus reveals a complex, cell type-specific landscape with novel regulatory elements
por: Taylor, Jennifer M., et al.
Publicado: (2008)

A high-throughput percentage-of-binding strategy to measure binding energies in DNA–protein interactions: application to genome-scale site discovery
por: Wang, Xiaohu, et al.
Publicado: (2008)

The splice variants of UBF differentially regulate RNA polymerase I transcription elongation in response to ERK phosphorylation
por: Stefanovsky, Victor Y., et al.
Publicado: (2008)

Sumoylation of LAP1 is involved in the HDAC4-mediated repression of COX-2 transcription
por: Wang, Wen-Ling, et al.
Publicado: (2008)

Context dependent function of APPb enhancer identified using enhancer trap-containing BACs as transgenes in zebrafish
por: Shakes, Leighcraft A., et al.
Publicado: (2008)

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
por: Jurkowska, Renata Z., et al.
Publicado: (2008)

Characterization of new regulatory elements within the Drosophila bithorax complex
por: Pérez-Lluch, Sílvia, et al.
Publicado: (2008)

Positional distribution of human transcription factor binding sites
por: Koudritsky, Mark, et al.
Publicado: (2008)

The 5′ end of two redundant sRNAs is involved in the regulation of multiple targets, including their own regulator
por: Guillier, Maude, et al.
Publicado: (2008)

Nonradioactive, ultrasensitive site-specific protein–protein photocrosslinking: interactions of α-helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2
por: Kim, Younggyu, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_t0moo6pmmtshl3d18a5s0onm77