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Exon Elongation Added Intrinsically Disordered Regions to the Encoded Proteins and Facilitated the Emergence of the Last Eukaryotic Common Ancestor

Most prokaryotic proteins consist of a single structural domain (SD) with little intrinsically disordered regions (IDRs) that by themselves do not adopt stable structures, whereas the typical eukaryotic protein comprises multiple SDs and IDRs. How eukaryotic proteins evolved to differ from prokaryot...

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Detalles Bibliográficos
Autores principales: Fukuchi, Satoshi, Noguchi, Tamotsu, Anbo, Hiroto, Homma, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825244/
https://www.ncbi.nlm.nih.gov/pubmed/36529689
http://dx.doi.org/10.1093/molbev/msac272