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Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma

BACKGROUND: Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis and limited understanding of the mechanism behind tumor invasion. Previous reports demonstrate upregulation of the protein ID1 with H3K27M and ACVR1 mutations in DMG, but thi...

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Detalles Bibliográficos
Autores principales: Messinger, Dana, Harris, Micah K, Cummings, Jessica R, Thomas, Chase, Yang, Tao, Sweha, Stefan R, Woo, Rinette, Siddaway, Robert, Burkert, Martin, Stallard, Stefanie, Qin, Tingting, Mullan, Brendan, Siada, Ruby, Ravindran, Ramya, Niculcea, Michael, Dowling, Abigail R, Bradin, Joshua, Ginn, Kevin F, Gener, Melissa A H, Dorris, Kathleen, Vitanza, Nicholas A, Schmidt, Susanne V, Spitzer, Jasper, Li, Jiang, Filbin, Mariella G, Cao, Xuhong, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Desprez, Pierre-Yves, McAllister, Sean, Dun, Matthew D, Hawkins, Cynthia, Waszak, Sebastian M, Venneti, Sriram, Koschmann, Carl, Yadav, Viveka Nand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825316/
https://www.ncbi.nlm.nih.gov/pubmed/35605606
http://dx.doi.org/10.1093/neuonc/noac141