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Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas
BACKGROUND: Malignant gliomas, the most common malignant brain tumors in adults, represent a heterogeneous group of diseases with poor prognosis. Retroviruses can cause permanent genetic alterations that modify genes close to the viral integration site. METHODS: Here we describe the use of a high-th...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825320/ https://www.ncbi.nlm.nih.gov/pubmed/35738865 http://dx.doi.org/10.1093/neuonc/noac158 |