Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

BACKGROUND: Malignant gliomas, the most common malignant brain tumors in adults, represent a heterogeneous group of diseases with poor prognosis. Retroviruses can cause permanent genetic alterations that modify genes close to the viral integration site. METHODS: Here we describe the use of a high-th...

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Detalles Bibliográficos
Autores principales: Weishaupt, Holger, Čančer, Matko, Rosén, Gabriela, Holmberg, Karl O, Häggqvist, Susana, Bunikis, Ignas, Jiang, Yiwen, Sreedharan, Smitha, Gyllensten, Ulf, Becher, Oren J, Uhrbom, Lene, Ameur, Adam, Swartling, Fredrik J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825320/
https://www.ncbi.nlm.nih.gov/pubmed/35738865
http://dx.doi.org/10.1093/neuonc/noac158

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