Role of microRNA in hydroxyurea mediated HbF induction in sickle cell anaemia patients

Hydroxyurea (HU) is found to be beneficial in sickle cell anaemia (SCA) patients, due to its ability to increase foetal haemoglobin (HbF), however, patients show a variable response. Differences in HbF levels are attributed to many factors; but, the role of miRNA in HbF regulation is sparsely invest...

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Detalles Bibliográficos
Autores principales: Kargutkar, Neha, Sawant-Mulay, Madhavi, Hariharan, Priya, Chandrakala, S., Nadkarni, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825386/
https://www.ncbi.nlm.nih.gov/pubmed/36611033
http://dx.doi.org/10.1038/s41598-022-25444-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825386/
https://www.ncbi.nlm.nih.gov/pubmed/36611033
http://dx.doi.org/10.1038/s41598-022-25444-3

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