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Role of microRNA in hydroxyurea mediated HbF induction in sickle cell anaemia patients
Hydroxyurea (HU) is found to be beneficial in sickle cell anaemia (SCA) patients, due to its ability to increase foetal haemoglobin (HbF), however, patients show a variable response. Differences in HbF levels are attributed to many factors; but, the role of miRNA in HbF regulation is sparsely invest...
Autores principales: | Kargutkar, Neha, Sawant-Mulay, Madhavi, Hariharan, Priya, Chandrakala, S., Nadkarni, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825386/ https://www.ncbi.nlm.nih.gov/pubmed/36611033 http://dx.doi.org/10.1038/s41598-022-25444-3 |
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