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HBV genotype-dependent association of HLA variants with the serodecline of HBsAg in chronic hepatitis B patients

Seroclearance of hepatitis B surface antigen (HBsAg) is regarded as the functional cure for chronic hepatitis B (CHB). The relationship between human leukocyte antigen (HLA) variants, hepatitis B virus genotype, and longitudinal HBsAg serodecline remains to be explored. A total of 1735 HBeAg-seroneg...

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Detalles Bibliográficos
Autores principales: Chu, Yu-Ju, Yang, Hwai-I., Hu, Hui-Han, Liu, Jessica, Lin, Yu-Ling, Chang, Chia-Ling, Luo, Wen-Sheng, Jen, Chin-Lan, Chen, Chien-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825396/
https://www.ncbi.nlm.nih.gov/pubmed/36611047
http://dx.doi.org/10.1038/s41598-023-27570-y