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Early response evaluation by single cell signaling profiling in acute myeloid leukemia

Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a cohort of 32 acute myeloid leukemia (AML) patients, using 36-dimensional mass cyt...

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Detalles Bibliográficos
Autores principales: Tislevoll, Benedicte Sjo, Hellesøy, Monica, Fagerholt, Oda Helen Eck, Gullaksen, Stein-Erik, Srivastava, Aashish, Birkeland, Even, Kleftogiannis, Dimitrios, Ayuda-Durán, Pilar, Piechaczyk, Laure, Tadele, Dagim Shiferaw, Skavland, Jørn, Baliakas, Panagotis, Hovland, Randi, Andresen, Vibeke, Seternes, Ole Morten, Tvedt, Tor Henrik Anderson, Aghaeepour, Nima, Gavasso, Sonia, Porkka, Kimmo, Jonassen, Inge, Fløisand, Yngvar, Enserink, Jorrit, Blaser, Nello, Gjertsen, Bjørn Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825407/
https://www.ncbi.nlm.nih.gov/pubmed/36611026
http://dx.doi.org/10.1038/s41467-022-35624-4