ABC-transporter CFTR folds with high fidelity through a modular, stepwise pathway

The question how proteins fold is especially pointed for large multi-domain, multi-spanning membrane proteins with complex topologies. We have uncovered the sequence of events that encompass proper folding of the ABC transporter CFTR in live cells by combining kinetic radiolabeling with protease-sus...

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Detalles Bibliográficos
Autores principales: Im, Jisu, Hillenaar, Tamara, Yeoh, Hui Ying, Sahasrabudhe, Priyanka, Mijnders, Marjolein, van Willigen, Marcel, Hagos, Azib, de Mattos, Eduardo, van der Sluijs, Peter, Braakman, Ineke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825563/
https://www.ncbi.nlm.nih.gov/pubmed/36609925
http://dx.doi.org/10.1007/s00018-022-04671-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825563/
https://www.ncbi.nlm.nih.gov/pubmed/36609925
http://dx.doi.org/10.1007/s00018-022-04671-x

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