Sibling variation in polygenic traits and DNA recombination mapping with UK Biobank and IVF family data

We use UK Biobank and a unique IVF family dataset (including genotyped embryos) to investigate sibling variation in both phenotype and genotype. We compare phenotype (disease status, height, blood biomarkers) and genotype (polygenic scores, polygenic health index) distributions among siblings to tho...

Descripción completa

Detalles Bibliográficos
Autores principales: Lello, Louis, Hsu, Maximus, Widen, Erik, Raben, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825593/
https://www.ncbi.nlm.nih.gov/pubmed/36611071
http://dx.doi.org/10.1038/s41598-023-27561-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825593/
https://www.ncbi.nlm.nih.gov/pubmed/36611071
http://dx.doi.org/10.1038/s41598-023-27561-z

Ejemplares similares