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Sibling variation in polygenic traits and DNA recombination mapping with UK Biobank and IVF family data
We use UK Biobank and a unique IVF family dataset (including genotyped embryos) to investigate sibling variation in both phenotype and genotype. We compare phenotype (disease status, height, blood biomarkers) and genotype (polygenic scores, polygenic health index) distributions among siblings to tho...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825593/ https://www.ncbi.nlm.nih.gov/pubmed/36611071 http://dx.doi.org/10.1038/s41598-023-27561-z |