A rapid RIG-I signaling relay mediates efficient antiviral response

RIG-I is essential for host defense against viral pathogens, as it triggers the release of type I interferons upon encounter with viral RNA molecules. In this study, we show that RIG-I is rapidly and efficiently activated by small quantities of incoming viral RNA and that it relies exclusively on th...

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Detalles Bibliográficos
Autores principales: Thoresen, Daniel T., Galls, Drew, Götte, Benjamin, Wang, Wenshuai, Pyle, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825657/
https://www.ncbi.nlm.nih.gov/pubmed/36521492
http://dx.doi.org/10.1016/j.molcel.2022.11.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825657/
https://www.ncbi.nlm.nih.gov/pubmed/36521492
http://dx.doi.org/10.1016/j.molcel.2022.11.018

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