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A rapid RIG-I signaling relay mediates efficient antiviral response
RIG-I is essential for host defense against viral pathogens, as it triggers the release of type I interferons upon encounter with viral RNA molecules. In this study, we show that RIG-I is rapidly and efficiently activated by small quantities of incoming viral RNA and that it relies exclusively on th...
Autores principales: | Thoresen, Daniel T., Galls, Drew, Götte, Benjamin, Wang, Wenshuai, Pyle, Anna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825657/ https://www.ncbi.nlm.nih.gov/pubmed/36521492 http://dx.doi.org/10.1016/j.molcel.2022.11.018 |
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