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Overexpression of Iron Super Oxide Dismutases A/B Genes Are Associated with Antimony Resistance of Leishmania tropica Clinical Isolates

BACKGROUND: Pentavalent antimonial has been a drug of choice against leishmaniasis, despite the emergence of treatment failure. Identification of resistance markers is urgently needed to design new therapeutic strategies. Iron-Superoxide dismutases (Fe-SODs) are antioxidant enzymes contributing to d...

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Detalles Bibliográficos
Autores principales: Bahrami, Afsane, Mohebali, Mehdi, Reisi Nafchi, Hossein, Raoofian, Reza, Kazemirad, Elham, Hajjaran, Homa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825701/
https://www.ncbi.nlm.nih.gov/pubmed/36694571
http://dx.doi.org/10.18502/ijpa.v17i4.11273