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PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data

MOTIVATION: Droplet digital PCR (ddPCR) holds great promises for investigating DNA methylation with high sensitivity. Yet, the lack of methods for analyzing ddPCR DNA methylation data has resulted in users processing the data manually at the expense of standardization. RESULTS: PoDCall is an R packa...

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Detalles Bibliográficos
Autores principales: Jeanmougin, Marine, Brodal, Hans Petter, Dietrichson Pharo, Heidi, Vedeld, Hege Marie, Lind, Guro Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825742/
https://www.ncbi.nlm.nih.gov/pubmed/36448696
http://dx.doi.org/10.1093/bioinformatics/btac766