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DeepCellEss: cell line-specific essential protein prediction with attention-based interpretable deep learning

MOTIVATION: Protein essentiality is usually accepted to be a conditional trait and strongly affected by cellular environments. However, existing computational methods often do not take such characteristics into account, preferring to incorporate all available data and train a general model for all c...

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Detalles Bibliográficos
Autores principales: Li, Yiming, Zeng, Min, Zhang, Fuhao, Wu, Fang-Xiang, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825760/
https://www.ncbi.nlm.nih.gov/pubmed/36458923
http://dx.doi.org/10.1093/bioinformatics/btac779