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DeepPHiC: predicting promoter-centered chromatin interactions using a novel deep learning approach

MOTIVATION: Promoter-centered chromatin interactions, which include promoter–enhancer (PE) and promoter–promoter (PP) interactions, are important to decipher gene regulation and disease mechanisms. The development of next-generation sequencing technologies such as promoter capture Hi-C (pcHi-C) lead...

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Detalles Bibliográficos
Autores principales: Agarwal, Aman, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825766/
https://www.ncbi.nlm.nih.gov/pubmed/36495179
http://dx.doi.org/10.1093/bioinformatics/btac801