bmVAE: a variational autoencoder method for clustering single-cell mutation data

MOTIVATION: Genetic intra-tumor heterogeneity (ITH) characterizes the differences in genomic variations between tumor clones, and accurately unmasking ITH is important for personalized cancer therapy. Single-cell DNA sequencing now emerges as a powerful means for deciphering underlying ITH based on...

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Detalles Bibliográficos
Autores principales: Yan, Jiaqian, Ma, Ming, Yu, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825778/
https://www.ncbi.nlm.nih.gov/pubmed/36478203
http://dx.doi.org/10.1093/bioinformatics/btac790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825778/
https://www.ncbi.nlm.nih.gov/pubmed/36478203
http://dx.doi.org/10.1093/bioinformatics/btac790

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