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bmVAE: a variational autoencoder method for clustering single-cell mutation data
MOTIVATION: Genetic intra-tumor heterogeneity (ITH) characterizes the differences in genomic variations between tumor clones, and accurately unmasking ITH is important for personalized cancer therapy. Single-cell DNA sequencing now emerges as a powerful means for deciphering underlying ITH based on...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825778/ https://www.ncbi.nlm.nih.gov/pubmed/36478203 http://dx.doi.org/10.1093/bioinformatics/btac790 |