The immunosuppression pathway of tumor‐associated macrophages is controlled by heme oxygenase‐1 in glioblastoma patients

The immunosuppressive tumor microenvironment (TME) in glioblastoma (GBM) is mainly driven by tumor‐associated macrophages (TAMs). We explored whether their sustained iron metabolism and immunosuppressive activity were correlated, and whether blocking the central enzyme of the heme catabolism pathway...

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Detalles Bibliográficos
Autores principales: Magri, Sara, Musca, Beatrice, Pinton, Laura, Orecchini, Elena, Belladonna, Maria Laura, Orabona, Ciriana, Bonaudo, Camilla, Volpin, Francesco, Ciccarino, Pietro, Baro, Valentina, Della Puppa, Alessandro, Mandruzzato, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Tumor Immunology and Microenvironment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825884/
https://www.ncbi.nlm.nih.gov/pubmed/36054818
http://dx.doi.org/10.1002/ijc.34270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825884/
https://www.ncbi.nlm.nih.gov/pubmed/36054818
http://dx.doi.org/10.1002/ijc.34270

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