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Total Synthesis and Functional Evaluation of IORs, Sulfonolipid‐based Inhibitors of Cell Differentiation in Salpingoeca rosetta

The choanoflagellate Salpingoeca rosetta is an important model system to study the evolution of multicellularity. In this study we developed a new, modular, and scalable synthesis of sulfonolipid IOR‐1A (six steps, 27 % overall yield), which acts as bacterial inhibitor of rosette formation in S. ros...

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Detalles Bibliográficos
Autores principales: Raguž, Luka, Peng, Chia‐Chi, Rutaganira, Florentine U. N., Krüger, Thomas, Stanišić, Aleksa, Jautzus, Theresa, Kries, Hajo, Kniemeyer, Olaf, Brakhage, Axel A., King, Nicole, Beemelmanns, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825905/
https://www.ncbi.nlm.nih.gov/pubmed/35901418
http://dx.doi.org/10.1002/anie.202209105