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Genome‐wide CRISPR‐Cas9 screen reveals a persistent null‐hyphal phenotype that maintains high carotenoid production in Yarrowia lipolytica

Yarrowia lipolytica is a metabolic engineering host of growing industrial interest due to its ability to metabolize hydrocarbons, fatty acids, glycerol, and other renewable carbon sources. This dimorphic yeast undergoes a stress‐induced transition to a multicellular hyphal state, which can negativel...

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Detalles Bibliográficos
Autores principales: Lupish, Brian, Hall, Jordan, Schwartz, Cory, Ramesh, Adithya, Morrison, Clifford, Wheeldon, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825908/
https://www.ncbi.nlm.nih.gov/pubmed/36042688
http://dx.doi.org/10.1002/bit.28219