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Removal of platelets from blood plasma to improve the quality of extracellular vesicle research

BACKGROUND: Blood plasma is commonly used for biomarker research of extracellular vesicles (EVs). Removing all cells prior to analysis of EVs is essential. OBJECTIVES: We therefore studied the efficacy of the most commonly used centrifugation protocol to prepare cell‐free plasma. METHODS: Plasma was...

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Detalles Bibliográficos
Autores principales: Bettin, Britta, Gasecka, Aleksandra, Li, Bo, Dhondt, Bert, Hendrix, An, Nieuwland, Rienk, van der Pol, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825910/
https://www.ncbi.nlm.nih.gov/pubmed/36043239
http://dx.doi.org/10.1111/jth.15867