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De novo assembly and annotation of the CHOZN® GS(−/−) genome supports high‐throughput genome‐scale screening

Chinese hamster ovary (CHO) cells have been used as the industry standard for the production of therapeutic monoclonal antibodies for several decades. Despite significant improvements in commercial‐scale production processes and media, the CHO cell has remained largely unchanged. Due to the cost and...

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Detalles Bibliográficos
Autores principales: Kretzmer, Corey, Narasimhan, Rajagopalan Lakshmi, Lal, Rahul Deva, Balassi, Vincent, Ravellette, James, Kotekar Manjunath, Ajaya Kumar, Koshy, Jesvin Joy, Viano, Marta, Torre, Serena, Zanda, Valeria M., Kumravat, Mausam, Saldanha, Keith Metelo Raul, Chandranpillai, Harikrishnan, Nihad, Ifra, Zhong, Fei, Sun, Yi, Gustin, Jason, Borgschulte, Trissa, Liu, Jiajian, Razafsky, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825924/
https://www.ncbi.nlm.nih.gov/pubmed/36073082
http://dx.doi.org/10.1002/bit.28226