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De novo assembly and annotation of the CHOZN® GS(−/−) genome supports high‐throughput genome‐scale screening
Chinese hamster ovary (CHO) cells have been used as the industry standard for the production of therapeutic monoclonal antibodies for several decades. Despite significant improvements in commercial‐scale production processes and media, the CHO cell has remained largely unchanged. Due to the cost and...
Autores principales: | Kretzmer, Corey, Narasimhan, Rajagopalan Lakshmi, Lal, Rahul Deva, Balassi, Vincent, Ravellette, James, Kotekar Manjunath, Ajaya Kumar, Koshy, Jesvin Joy, Viano, Marta, Torre, Serena, Zanda, Valeria M., Kumravat, Mausam, Saldanha, Keith Metelo Raul, Chandranpillai, Harikrishnan, Nihad, Ifra, Zhong, Fei, Sun, Yi, Gustin, Jason, Borgschulte, Trissa, Liu, Jiajian, Razafsky, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825924/ https://www.ncbi.nlm.nih.gov/pubmed/36073082 http://dx.doi.org/10.1002/bit.28226 |
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