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Group sequential methods for interim monitoring of randomized clinical trials with time‐lagged outcome

The primary analysis in two‐arm clinical trials usually involves inference on a scalar treatment effect parameter; for example, depending on the outcome, the difference of treatment‐specific means, risk difference, risk ratio, or odds ratio. Most clinical trials are monitored for the possibility of...

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Detalles Bibliográficos
Autores principales: Tsiatis, Anastasios A., Davidian, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825950/
https://www.ncbi.nlm.nih.gov/pubmed/36117235
http://dx.doi.org/10.1002/sim.9580