APOE ε4 influences cognitive decline positively in APP and negatively in PSEN1 mutation carriers with autosomal‐dominant Alzheimer's disease

BACKGROUND AND PURPOSE: The aim was to investigate the effect of APOE ε4 allele on cognitive decline in adAD. Presence of the APOE ε4 allele reduces age of symptom onset, increases disease progression, and lowers cognitive performance in sporadic Alzheimer's disease (AD), while the impact of th...

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Detalles Bibliográficos
Autores principales: Almkvist, Ove, Johansson, Charlotte, Laffita‐Mesa, Jose, Thordardottir, Steinunn, Graff, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Movement Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826049/
https://www.ncbi.nlm.nih.gov/pubmed/36039401
http://dx.doi.org/10.1111/ene.15536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826049/
https://www.ncbi.nlm.nih.gov/pubmed/36039401
http://dx.doi.org/10.1111/ene.15536

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