Loss of ALK hotspot mutations in relapsed neuroblastoma

ALK is the most commonly mutated oncogene in neuroblastoma with increased mutation frequency reported at relapse. Here we report the loss of an ALK mutation in two patients at relapse and a paired neuroblastoma cell line at relapse. ALK detection methods including Sanger sequencing, targeted next‐ge...

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Detalles Bibliográficos
Autores principales: Allinson, Lisa M., Potts, Aaron, Goodman, Angharad, Bown, Nick, Bashton, Matthew, Thompson, Dean, Basta, Nermine O., Gabriel, Alem S., McCorkindale, Michael, Ng, Antony, McNally, Richard J. Q., Tweddle, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826054/
https://www.ncbi.nlm.nih.gov/pubmed/36029175
http://dx.doi.org/10.1002/gcc.23093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826054/
https://www.ncbi.nlm.nih.gov/pubmed/36029175
http://dx.doi.org/10.1002/gcc.23093

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