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Loss of ALK hotspot mutations in relapsed neuroblastoma
ALK is the most commonly mutated oncogene in neuroblastoma with increased mutation frequency reported at relapse. Here we report the loss of an ALK mutation in two patients at relapse and a paired neuroblastoma cell line at relapse. ALK detection methods including Sanger sequencing, targeted next‐ge...
Autores principales: | Allinson, Lisa M., Potts, Aaron, Goodman, Angharad, Bown, Nick, Bashton, Matthew, Thompson, Dean, Basta, Nermine O., Gabriel, Alem S., McCorkindale, Michael, Ng, Antony, McNally, Richard J. Q., Tweddle, Deborah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826054/ https://www.ncbi.nlm.nih.gov/pubmed/36029175 http://dx.doi.org/10.1002/gcc.23093 |
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