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Using Macrocyclic G‐Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G‐Quadruplex DNA

This study aims to deepen the knowledge of the current state of rational G4‐ligand design through the design and synthesis of a novel set of compounds based on indoles, quinolines, and benzofurans and their comparisons with well‐known G4‐ligands. This resulted in novel synthetic methods and G4‐ligan...

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Detalles Bibliográficos
Autores principales: Andréasson, Måns, Bhuma, Naresh, Pemberton, Nils, Chorell, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826068/
https://www.ncbi.nlm.nih.gov/pubmed/35997141
http://dx.doi.org/10.1002/chem.202202020