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Shock and kill within the CNS: A promising HIV eradication approach?

The most studied HIV eradication approach is the “shock and kill” strategy, which aims to reactivate the latent reservoir by latency reversing agents (LRAs) and allowing elimination of these cells by immune‐mediated clearance or viral cytopathic effects. The CNS is an anatomic compartment in which (...

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Detalles Bibliográficos
Autores principales: Nühn, Marieke M., Gumbs, Stephanie B. H., Buchholtz, Ninée V. E. J., Jannink, Lisanne M., Gharu, Lavina, de Witte, Lot D., Wensing, Annemarie M. J., Lewin, Sharon R., Nijhuis, Monique, Symons, Jori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826147/
https://www.ncbi.nlm.nih.gov/pubmed/36148896
http://dx.doi.org/10.1002/JLB.5VMR0122-046RRR