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Causal inference for planning randomised critical care trials: Protocol for a scoping review

BACKGROUND: Randomised clinical trials in critical care are prone to inconclusiveness owing, in part, to undue optimism about effect sizes and suboptimal accounting for heterogeneous treatment effects. Planned predictive enrichment based on secondary critical care data (often very rich with respect...

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Detalles Bibliográficos
Autores principales: Kaas‐Hansen, Benjamin Skov, Granholm, Anders, Anthon, Carl Thomas, Kjær, Maj‐Brit Nørregaard, Sivapalan, Praleene, Maagaard, Mathias, Schjørring, Olav Lilleholt, Fagerberg, Steen Kåre, Ellekjær, Karen Louise, Mølgaard, Jesper, Ekstrøm, Claus Thorn, Møller, Morten Hylander, Perner, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826202/
https://www.ncbi.nlm.nih.gov/pubmed/36054374
http://dx.doi.org/10.1111/aas.14142