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Variable serotonin release assay pattern and specificity of PF4‐specific antibodies in HIT, and clinical relevance
BACKGROUND: The diagnosis of heparin‐induced thrombocytopenia (HIT) requires functional assays to demonstrate that platelet factor 4 (PF4)‐specific antibodies activate platelets, typically when therapeutic heparin (H) concentrations are tested (“classical” pattern). Some HIT samples also activate pl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826218/ https://www.ncbi.nlm.nih.gov/pubmed/35971886 http://dx.doi.org/10.1111/jth.15848 |