Variable serotonin release assay pattern and specificity of PF4‐specific antibodies in HIT, and clinical relevance

BACKGROUND: The diagnosis of heparin‐induced thrombocytopenia (HIT) requires functional assays to demonstrate that platelet factor 4 (PF4)‐specific antibodies activate platelets, typically when therapeutic heparin (H) concentrations are tested (“classical” pattern). Some HIT samples also activate pl...

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Detalles Bibliográficos
Autores principales: Rollin, Jérôme, Charuel, Noémie, Gruel, Yves, Billy, Sandra, Guéry, Eve‐Anne, May, Marc‐Antoine, Pouplard, Claire, Vayne, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
PLATELETS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826218/
https://www.ncbi.nlm.nih.gov/pubmed/35971886
http://dx.doi.org/10.1111/jth.15848

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