Synthesis, Biological Evaluation, and Binding Mode of a New Class of Oncogenic K‐Ras4b Inhibitors

Ras proteins are implicated in some of the most common life‐threatening cancers. Despite intense research during the past three decades, progress towards small‐molecule inhibitors of mutant Ras proteins still has been limited. Only recently has significant progress been made, in particular with liga...

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Detalles Bibliográficos
Autores principales: Jeuken, Stephan, Shkura, Oleksandr, Röger, Marc, Brickau, Victoria, Choidas, Axel, Degenhart, Carsten, Gülden, Daniel, Klebl, Bert, Koch, Uwe, Stoll, Raphael, Scherkenbeck, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826232/
https://www.ncbi.nlm.nih.gov/pubmed/35979853
http://dx.doi.org/10.1002/cmdc.202200392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826232/
https://www.ncbi.nlm.nih.gov/pubmed/35979853
http://dx.doi.org/10.1002/cmdc.202200392

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