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Synthesis, Biological Evaluation, and Binding Mode of a New Class of Oncogenic K‐Ras4b Inhibitors
Ras proteins are implicated in some of the most common life‐threatening cancers. Despite intense research during the past three decades, progress towards small‐molecule inhibitors of mutant Ras proteins still has been limited. Only recently has significant progress been made, in particular with liga...
Autores principales: | Jeuken, Stephan, Shkura, Oleksandr, Röger, Marc, Brickau, Victoria, Choidas, Axel, Degenhart, Carsten, Gülden, Daniel, Klebl, Bert, Koch, Uwe, Stoll, Raphael, Scherkenbeck, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826232/ https://www.ncbi.nlm.nih.gov/pubmed/35979853 http://dx.doi.org/10.1002/cmdc.202200392 |
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