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Protein kinase C‐mediated phosphorylation of transient receptor potential melastatin type 2 Thr738 counteracts the effect of cytosolic Ca(2+) and elevates the temperature threshold
ABSTRACT: The transient receptor potential melastatin type 2 (TRPM2) channel is a non‐selective cation channel that has high Ca(2+) permeability. TRPM2 is sensitive to warm temperatures and is expressed in cells and tissues that are maintained at core body temperature. TRPM2 activity is also regulat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826287/ https://www.ncbi.nlm.nih.gov/pubmed/36042566 http://dx.doi.org/10.1113/JP283350 |