Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle

BACKGROUND AND PURPOSE: Donepezil, a piperidine inhibitor of acetylcholinesterase (AChE) prescribed for treatment of Alzheimer's disease, has adverse neuromuscular effects in humans, including requirement for higher concentrations of non‐depolarising neuromuscular blockers during surgery. Here,...

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Detalles Bibliográficos
Autores principales: Redman, Robert R., Mackenzie, Harry, Dissanayake, Kosala N., Eddleston, Michael, Ribchester, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826304/
https://www.ncbi.nlm.nih.gov/pubmed/36028305
http://dx.doi.org/10.1111/bph.15940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826304/
https://www.ncbi.nlm.nih.gov/pubmed/36028305
http://dx.doi.org/10.1111/bph.15940

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