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Skin inflammation and impaired adipogenesis in a mouse model of acid ceramidase deficiency

Acid ceramidase catalyzes the degradation of ceramide into sphingosine and a free fatty acid. Acid ceramidase deficiency results in lipid accumulation in many tissues and leads to the development of Farber disease (FD). Typical manifestations of classical FD include formation of subcutaneous nodules...

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Detalles Bibliográficos
Autores principales: Rybova, Jitka, Kuchar, Ladislav, Sikora, Jakub, McKillop, William M., Medin, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826362/
https://www.ncbi.nlm.nih.gov/pubmed/36083604
http://dx.doi.org/10.1002/jimd.12552