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Photochromic Fentanyl Derivatives for Controlled μ‐Opioid Receptor Activation

Photoswitchable ligands as biological tools provide an opportunity to explore the kinetics and dynamics of the clinically relevant μ‐opioid receptor. These ligands can potentially activate or deactivate the receptor when desired by using light. Spatial and temporal control of biological activity all...

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Detalles Bibliográficos
Autores principales: Lahmy, Ranit, Hübner, Harald, Schmidt, Maximilian F., Lachmann, Daniel, Gmeiner, Peter, König, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826449/
https://www.ncbi.nlm.nih.gov/pubmed/35899620
http://dx.doi.org/10.1002/chem.202201515