Diterpene Biosynthesis from Geranylgeranyl Diphosphate Analogues with Changed Reactivities Expands Skeletal Diversity

Two analogues of the diterpene precursor geranylgeranyl diphosphate with shifted double bonds, named iso‐GGPP I and iso‐GGPP II, were enzymatically converted with twelve diterpene synthases from bacteria, fungi and protists. The changed reactivity in the substrate analogues resulted in the formation...

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Detalles Bibliográficos
Autores principales: Li, Heng, Dickschat, Jeroen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826473/
https://www.ncbi.nlm.nih.gov/pubmed/36066489
http://dx.doi.org/10.1002/anie.202211054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826473/
https://www.ncbi.nlm.nih.gov/pubmed/36066489
http://dx.doi.org/10.1002/anie.202211054

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