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Diterpene Biosynthesis from Geranylgeranyl Diphosphate Analogues with Changed Reactivities Expands Skeletal Diversity
Two analogues of the diterpene precursor geranylgeranyl diphosphate with shifted double bonds, named iso‐GGPP I and iso‐GGPP II, were enzymatically converted with twelve diterpene synthases from bacteria, fungi and protists. The changed reactivity in the substrate analogues resulted in the formation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826473/ https://www.ncbi.nlm.nih.gov/pubmed/36066489 http://dx.doi.org/10.1002/anie.202211054 |