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Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1

BACKGROUND: Osteosarcoma (OS) is the most frequent cancer derived from bone, and the prognosis of OS is poor. Metabolic alterations have been previously reported to contribute to the development of OS, and arsenic compounds have been suggested to exhibit strong anti-OS effects. However, few studies...

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Detalles Bibliográficos
Autores principales: Liu, Yixin, She, Wenyan, Li, Yi, Wang, Miao, Liu, Yin, Ning, Biao, Xu, Tianzi, Huang, Tianhe, Wei, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826572/
https://www.ncbi.nlm.nih.gov/pubmed/36611209
http://dx.doi.org/10.1186/s12967-022-03862-1