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EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage

OBJECTIVE: Targeting deubiquitinases (DUBs) has emerged as a promising avenue for anticancer drug development. However, the effect and mechanism of pan-DUB inhibitor EOAI on non-small cell lung cancer (NSCLC) remains to be studied. MATERIALS AND METHODS: The expression of ubiquitin-specific peptidas...

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Detalles Bibliográficos
Autores principales: Zheng, Yuanyuan, Wang, Longhao, Niu, Xiaoyu, Guo, Yongjun, Zhao, Jiuzhou, Li, Lifeng, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826599/
https://www.ncbi.nlm.nih.gov/pubmed/36611139
http://dx.doi.org/10.1186/s12885-023-10506-0