Epigenetically suppressed tumor cell intrinsic STING promotes tumor immune escape

DNA sensing through the cGAS-STING pathway plays an important role in cancer immunosurveillance. Pharmaceutical activation of STING in the tumor environment is considered an attractive approach to induce antitumor immunity, but had limited efficacy in the clinic. Several studies have found that STIN...

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Detalles Bibliográficos
Autores principales: Zheng, Hui, Wu, Lizhen, Xiao, Qian, Meng, Xin, Hafiz, Alex, Yan, Qin, Lu, Renquan, Cao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826630/
https://www.ncbi.nlm.nih.gov/pubmed/36436495
http://dx.doi.org/10.1016/j.biopha.2022.114033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826630/
https://www.ncbi.nlm.nih.gov/pubmed/36436495
http://dx.doi.org/10.1016/j.biopha.2022.114033

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